Spurious hypophosphatemia associated with monoclonal paraproteinemia
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منابع مشابه
Case report Spurious hypophosphatemia associated with monoclonal paraproteinemia
Hypophosphatemia is a relatively uncommon finding in clinical practice, with a prevalence of 1–5% in all hospitalized patients. However, it is an adverse prognostic marker for mortality and morbidity. Although the correlation between serum phosphate levels and symptoms is not linear, severe hypophosphatemia is important to recognize and treat since it can lead to rhabdomyolysis, haemolysis, res...
متن کاملHypophosphatemia associated with paraproteinemia: a case report and review of the literature.
The differential diagnosis for hypophosphatemia is long, and involves complex, overlapping physiological systems. Practitioners are often guilty, however, of simply supplementing phosphate without fully investigating the etiology of the problem. The purpose of this case presentation is to illustrate a case of spurious hypophosphatemia that initially led to unnecessary phosphate replacement in a...
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BACKGROUND Renal disease associated with paraproteinemias is classically predicated upon pathologic paraprotein deposition in the kidney. However, growing evidence suggests that paraproteins may be able to systemically activate complement or neutrophils to drive renal damage. This may provide an alternative pathologic mechanism for renal injury in rare cases. CASE REPORT We report a case of a...
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M ONOCLONAL gammopathies are commonly associated with multiple myeloma and Waldenstr#{246}m's macroglobulinemia. These diseases generally occur only in older age groups. Paraproteinemias have also been oh-served in myeloproliferative disorders,1 as well as in association with lympho-mas.2 However, paraproteinemia in children is an extremely rare condition, and only very few cases have been reco...
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There is increasing evidence that monoclonal proteins are implicated in the development of peripheral neuropathy. Approximately ten percent of patients with peripheral neuropathy of unknown cause have a monoclonal protein and this rate is significantly higher than prevalence rates of monoclonal protein in comparable segments of the general population. Extensive clinical, electrophysiological an...
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ژورنال
عنوان ژورنال: QJM
سال: 2011
ISSN: 1460-2725,1460-2393
DOI: 10.1093/qjmed/hcr104